Mech DAMP Blog

Mathematical Modeling and Simulation of Biological Tumors

 Mathematical Modeling and Simulation of Biological Tumors

Aditya Agarwal

Guiding Professor and University

Dnyanesh Pawaskar, IIT Bombay

Project Title

Mathematical Modeling and Simulation of Biological Tumors

Field

Solid mechanics + Biology

How did you reach out to the prof?

Got selected through In-Semester Undergraduate Research Programme (ISURP)

How did you prepare for your first meeting with the prof? What previous knowledge was required?

Prepared basic concepts of solid mechanics.

What was the research topic? How did you arrive at it? (did the prof give it/did you explore & find it yourself)

Modeled necrotic core temperature and flux distributions, enhancing tumor behaviour understanding

What was the duration of the project?

Dec’23-Apr’24

What was the work done by you as part of the project? Who were the other stakeholders involved?

•Utilized FEM simulations in ANSYS, achieving 98% accuracy in modeling tumor temperature distribution • Identified the impact of compressive stress on tumor growth dynamics within the immediate environment

Carried out project with Dhriti Maniar

What was the mentorship style like and how often did you meet with the professor?

Weekly meetings, slow paced since it was a semester long project.

How was the overall experience? (Key learnings & Challenges)

The main challenge was to learn Ansys software. It took alot of time to figure out its features and use it for our own purpose. Got to learn a great blend of solid mechanics and biology.

What are the future plans following this project?

Not much scope in continuing this project further

What challenges you faced during the project?

I took up two remote research projects during summer of 2024 which became a bit tedious at one point because the expectations grew after deciding to go for a publication for Melbourne work. Though I got accepted by 5 universities, I chose melbourne and CMU due to their high QS ranking and sufficient gaps in time zones to prevent clashes.